Description

9-Cis Retinoyl B-D-Glucuronide is a glucuronidated metabolite of 9-cis-retinoic acid, a biologically active retinoid. This compound is significant for its role in retinoid metabolism and transport, offering enhanced water solubility compared to its parent compound. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug metabolism studies, analytical reference standards, and the development of novel therapeutic agents targeting retinoid pathways.

Application

• Pharmaceutical Research & Development: Used as a key reference standard in the study of retinoid metabolism, pharmacokinetics, and bioavailability.
• Analytical Chemistry: Serves as a high-purity calibrant or internal standard for HPLC, LC-MS, and other chromatographic methods in bioanalytical labs.
• Biochemical Studies: Employed in in vitro and ex vivo experiments to investigate the activity and transport mechanisms of retinoid glucuronides.
• Cosmeceutical R&D: Investigated for potential applications in advanced skincare formulations targeting cellular differentiation and renewal.
• Metabolite Synthesis: Acts as a crucial intermediate or target molecule in the synthetic pathways for specialized retinoid metabolites.

Basic Information

Product Name	9-Cis Retinoyl B-D-Glucuronide
CAS No.	153321-67-6
Molecular Formula	C26H34O9
Molecular Weight	490.54 g/mol
Synonyms	9-cis-Retinoyl-β-D-glucuronide; (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoyl β-D-Glucopyranosiduronic Acid; 9-cis-Retinoic Acid β-D-Glucuronide; 9cRA-Glucuronide; β-D-Glucopyranosiduronic acid, (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid, 1-(hydrogen sulfate); 9-cis Retinoyl glucuronide
EINECS	Contact for details

Quality Control

Our 9-Cis Retinoyl B-D-Glucuronide is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR). We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring compliance with research and development standards. Custom purity grades and analytical services are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. For long-term storage, keep the material desiccated to prevent moisture uptake. Allow the sealed container to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.