Description

U-74389G CAS NO 153190-29-5 is a high-purity, specialized chemical compound belonging to the lazaroid (21-aminosteroid) class, known for its potent antioxidant and anti-inflammatory properties. This compound is critical for advanced research and development in fields requiring the inhibition of lipid peroxidation and protection against oxidative stress. It is primarily utilized by pharmaceutical researchers, biochemists, and material scientists working on neuroprotection, ischemia-reperfusion injury, and novel therapeutic agent development.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the study of neuroprotective agents and treatments for traumatic brain injury.
• Biochemical Research: Used in in vitro and in vivo studies to investigate mechanisms of lipid peroxidation and cellular damage from free radicals.
• Academic & Institutional Research: Serves as a critical tool compound in university and institutional labs for neuroscience, cardiology, and toxicology research programs.
• Preclinical Development: Employed in the formulation and efficacy testing of new drug candidates targeting oxidative stress-related disorders.
• Chemical Synthesis: Acts as a sophisticated building block for the synthesis of novel steroid-derived compounds with enhanced biological activity.
• Quality Control & Analytical Standards: Used as a certified reference material (CRM) in analytical laboratories for method development and validation.

Basic Information

Product Name	U-74389G
CAS No.	153190-29-5
Molecular Formula	C33H59N3O5
Molecular Weight	577.84 g/mol
Synonyms	U-74389G; 21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-16-methylpregna-5,14-diene-3,20-dione; Lazaroid U-74389G; 21-[4-(2,6-Di(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl]-16-methylpregna-5,14-diene-3,20-dione; Pregn-5,14-diene-3,20-dione, 21-[4-[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl]-16-methyl-; U74389G
EINECS	Contact for details

Quality Control

Our U-74389G is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.