Description

2-Fluoro-3-Iodo-5-Methylpyridine is a high-value halogenated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by research institutions and industrial R&D departments focused on developing new active ingredients, including kinase inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in the development of targeted therapies and kinase inhibitors.
• Agrochemical Research: Used in the creation of new pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for functionalized ligands and organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form biaryl systems.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.

Basic Information

Product Name	2-Fluoro-3-Iodo-5-Methylpyridine
CAS No.	153034-78-7
Molecular Formula	C6H5FIN
Molecular Weight	237.01 g/mol
Synonyms	3-Iodo-2-fluoro-5-methylpyridine; 5-Methyl-2-fluoro-3-iodopyridine; 2-Fluoro-3-iodo-5-picoline; Pyridine, 2-fluoro-3-iodo-5-methyl-; 153034-78-7
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodo-5-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.