Description

Trypsin Carboxypeptidase Peptide Inhibitor CAS NO 152787-59-2 is a potent, selective, and reversible inhibitor of trypsin and carboxypeptidase B, designed to block the enzymatic activity of these proteases. This compound is critical for controlling proteolytic degradation in sensitive biochemical and biopharmaceutical processes, ensuring sample integrity and experimental reproducibility. It is an essential research tool for enzymologists, molecular biologists, and process development scientists working in pharmaceutical R&D, bioprocessing, and diagnostic assay development.

Application

• Biopharmaceutical Manufacturing: Used to inhibit proteases during the downstream purification of recombinant proteins, monoclonal antibodies, and other biologics to prevent product degradation.
• Enzymology Research: Serves as a specific tool compound for studying the kinetics, structure, and function of serine proteases like trypsin and metallocarboxypeptidases.
• Diagnostic Reagent Formulation: Incorporated into diagnostic kits and assay buffers to stabilize reagents and prevent false results caused by protease activity.
• Cell Culture & Tissue Engineering: Applied in research to control extracellular matrix remodeling by inhibiting specific proteases during cell culture experiments.
• Sample Preparation for Proteomics: Utilized to quench protease activity in tissue lysates, serum, or other biological samples prior to mass spectrometry or gel electrophoresis analysis.
• Stabilizer for Labile Peptides: Added to solutions containing synthetic or natural peptides to extend their shelf-life by inhibiting proteolytic cleavage.

Basic Information

Product Name	Trypsin Carboxypeptidase Peptide Inhibitor
CAS No.	152787-59-2
Molecular Formula	C23H39N7O6
Molecular Weight	509.60 g/mol
Synonyms	Benzyloxycarbonyl-Gly-Pro; Z-Gly-Pro; Z-Gly-Pro-OH; Cbz-Gly-Pro; Carbobenzoxy-glycyl-proline; N-Carbobenzoxyglycyl-L-proline; N-[(Benzyloxy)carbonyl]glycyl-L-proline; Gly-Pro Z
EINECS	Contact for details

Quality Control

Our Trypsin Carboxypeptidase Peptide Inhibitor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring high-purity biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which may affect stability and performance. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details
Biological Activity (IC50)	Provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.