Description

(+)-1-Decarboxy-1-Methyl-20-Nor-19-Carboxyprostaglandin F(2α) is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is critical for its role in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing treatments for conditions related to prostaglandin activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel prostaglandin-based drug candidates.
• Biochemical Research: Used as a reference standard and active compound in studies investigating prostaglandin receptor interactions and signaling pathways.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs aimed at developing new therapeutics for inflammation, ocular hypertension, or reproductive health.
• Process Development: Employed in the scale-up and optimization of synthetic routes for prostaglandin analogs under Good Manufacturing Practice (GMP) conditions.
• Analytical Standard: Used for method development, validation, and quality control (HPLC, LC-MS) in analytical laboratories.

Basic Information

Product Name	(+)-1-Decarboxy-1-Methyl-20-Nor-19-Carboxyprostaglandin F(2α)
CAS No.	152561-64-3
Molecular Formula	C₂₁H₃₄O₅
Molecular Weight	366.5 g/mol
Synonyms	1-Decarboxy-1-methyl-20-nor-19-carboxy-PGF2α; 17-Phenyl-18,19,20-trinorprostaglandin F2α 1-methyl ester derivative; Travoprost related compound; Prostaglandin F2α analog; 9,11,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-dien-1-oic acid methyl ester; AL-6221; AL6221
EINECS	Contact for details

Quality Control

Our (+)-1-Decarboxy-1-Methyl-20-Nor-19-Carboxyprostaglandin F(2α) is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.