Description

Benzyloxycarbonyl-Alanyl-Alanyl-Prolyl-Phenylalanine-Trifluoromethylketone is a synthetic peptide derivative designed as a potent and selective protease inhibitor. This compound is of significant value in biochemical and pharmaceutical research for studying enzyme mechanisms and developing therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and biotechnology companies focused on protease-targeted drug discovery and biochemical pathway analysis.

Application

• Protease Inhibition Research: Serves as a key biochemical tool for investigating the activity and inhibition kinetics of specific serine or cysteine proteases.
• Drug Discovery & Development: Used as a lead compound or intermediate in the design and synthesis of novel therapeutic agents targeting proteolytic enzymes.
• Biochemical Assay Standard: Acts as a reference standard in enzymatic assays to validate experimental models and test protocols.
• Mechanistic Studies: Employed in academic and industrial research to elucidate the structure-activity relationships (SAR) of protease inhibitors.
• Peptide Chemistry: Utilized as a specialized building block in advanced peptide synthesis for creating complex bioactive molecules.

Basic Information

Product Name	Benzyloxycarbonyl-Alanyl-Alanyl-Prolyl-Phenylalanine-Trifluoromethylketone
CAS No.	152551-55-8
Molecular Formula	C33H39F3N4O7
Molecular Weight	660.68 g/mol
Synonyms	Z-AAPF-CF3; Z-Ala-Ala-Pro-Phe-CF3; Cbz-AAPF-trifluoromethyl ketone; Benzyloxycarbonyl-Ala-Ala-Pro-Phe-CF3; Ala-Ala-Pro-Phe(Cbz) trifluoromethylketone; Protease Inhibitor 152551-55-8; Z-AAPF-trifluoroketone; N-Benzyloxycarbonyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our Benzyloxycarbonyl-Alanyl-Alanyl-Prolyl-Phenylalanine-Trifluoromethylketone is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.