Description

4-Pyridinecarboxamide,3-Fluoro-(9Ci) is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and pyridine core impart specific biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of fluorinated drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the fluorine atom to enhance bioavailability and environmental persistence.
• Ligand & Catalyst Development: Acts as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Utilized as a probe or labeling agent in biochemical research due to its fluorinated structure.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific fluorinated heterocycles.

Basic Information

Product Name	4-Pyridinecarboxamide,3-Fluoro-(9Ci)
CAS No.	152126-30-2
Molecular Formula	C6H5FN2O
Molecular Weight	140.12 g/mol
Synonyms	3-Fluoropyridine-4-carboxamide; 3-Fluoroisonicotinamide; 3-Fluoro-4-pyridinecarboxamide; 3-Fluoropyridine-4-carboxylic acid amide; 4-Carbamoyl-3-fluoropyridine; 3-Fluoro-4-carbamoylpyridine; 3-Fluoropyridine-4-carboxylic acid, amide; 3-Fluoroisonicotinic acid amide
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxamide,3-Fluoro-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.