Description

Iron Chelator, Dp44Mt is a potent and selective synthetic chelating agent designed for the sequestration of labile iron. This compound is of significant interest in biochemical and pharmaceutical research for its ability to modulate iron-dependent processes. It is primarily utilized by researchers and developers in the fields of neurobiology, oncology, and molecular biology to study iron metabolism, oxidative stress, and related disease pathways.

Application

• Biomedical Research: Investigation of iron's role in neurodegenerative diseases (e.g., Alzheimer's, Parkinson's), cancer cell proliferation, and ferroptosis.
• Mechanistic Studies: Used as a tool compound to inhibit iron-catalyzed reactions and study oxidative damage in cellular and in vitro models.
• Pharmaceutical Development: Serves as a reference standard and a lead compound in the discovery of novel iron-chelating therapeutics.
• Biochemistry: Chelation of free iron in buffer systems and experimental setups to prevent metal-catalyzed degradation of sensitive biomolecules.

Basic Information

Product Name	Iron Chelator, Dp44Mt
CAS No.	152095-12-0
Molecular Formula	C20H22N4O2
Molecular Weight	350.42 g/mol
Synonyms	Dp44mT; Dp-44mT; 2-[(2-Hydroxy-4-methoxyphenyl)methylene]-N-(2-pyridinylmethyl)hydrazinecarbothioamide; 2-(2-Hydroxy-4-methoxybenzylidene)-N-(pyridin-2-ylmethyl)hydrazine-1-carbothioamide; Di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (common structural family reference); Iron Chelator 44mT; Thiosemicarbazone Chelator Dp44mT
EINECS	Contact for details

Quality Control

Our research-grade Dp44Mt is produced under strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identification (IR, NMR), and other relevant parameters is provided with every shipment to support your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.