Description

5-Fluoro-1-Methyl-3-Trifluoromethyl-1H-Pyrazole-4-Carboxylic Acid is a high-value fluorinated pyrazole derivative, a key building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and a trifluoromethyl group, makes it an essential intermediate for creating compounds with enhanced biological activity and metabolic stability. This product is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors, anti-inflammatory, and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms improve lipophilicity and target binding.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to materials with specific optical or electronic properties.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Fluoro-1-Methyl-3-Trifluoromethyl-1H-Pyrazole-4-Carboxylic Acid
CAS No.	151734-01-9
Molecular Formula	C7H4F4N2O2
Molecular Weight	224.11 g/mol
Synonyms	5-Fluoro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; 4-Pyrazolecarboxylic acid, 5-fluoro-1-methyl-3-(trifluoromethyl)-1H-; 1-Methyl-5-fluoro-3-trifluoromethylpyrazole-4-carboxylic acid; 5-Fluoro-1-methyl-3-trifluoromethylpyrazole-4-carboxylic acid; 151734-01-9; 5-Fluoro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 5-fluoro-1-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 5-Fluoro-1-Methyl-3-Trifluoromethyl-1H-Pyrazole-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, and our quality systems support compliance with cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.