Description

Dephostatin CAS NO 151606-30-3 is a potent and selective inhibitor of protein tyrosine phosphatases (PTPs), specifically targeting dual-specificity phosphatases. This compound is a critical research tool for studying cellular signaling pathways, particularly those involving tyrosine phosphorylation and dephosphorylation cycles. It is essential for researchers and developers in the fields of biochemistry, oncology, and neurobiology, where precise modulation of PTP activity is required to investigate disease mechanisms and potential therapeutic targets.

Application

• Biochemical Research: A key reagent for in vitro and cell-based studies to inhibit specific protein tyrosine phosphatases, elucidating their role in signal transduction.
• Oncology Research: Used to investigate tumor suppressor pathways and oncogenic signaling networks influenced by tyrosine dephosphorylation.
• Neuroscience Studies: Applied in research on neural development, synaptic plasticity, and neurodegenerative diseases where PTP activity is implicated.
• Drug Discovery: Serves as a pharmacological probe and a lead compound in the development of novel therapeutic agents targeting phosphatase-related disorders.
• Cell Biology: Utilized to study cell cycle regulation, differentiation, and apoptosis by modulating specific phosphatase activity.

Basic Information

Product Name	Dephostatin
CAS No.	151606-30-3
Molecular Formula	C₁₄H₁₀N₂O₄
Molecular Weight	270.24 g/mol
Synonyms	Dephostatin; NSC 339313; 2,5-Dihydroxy-N-(2-hydroxy-5-nitrophenyl)benzamide; 2,5-Dihydroxy-N-(2-hydroxy-5-nitrophenyl)benzenecarboxamide; PTP Inhibitor Dephostatin; Protein Tyrosine Phosphatase Inhibitor Dephostatin
EINECS	Contact for details

Quality Control

Our Dephostatin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals, ensuring reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.