Description

Pironetin CAS NO 151519-02-7 is a potent, naturally occurring polyketide compound with significant biological activity. This molecule is of high interest due to its unique mechanism of action as a microtubule inhibitor, which makes it a valuable tool in biochemical and pharmacological research. It is primarily sought after by research institutions and pharmaceutical companies engaged in anticancer drug discovery, cell biology studies, and the development of novel therapeutic agents targeting the cytoskeleton.

Application

• Anticancer Research: As a potent microtubule-destabilizing agent for studying cell cycle arrest, apoptosis, and mechanisms of drug resistance.
• Chemical Biology: A critical probe for investigating tubulin dynamics, protein-protein interactions, and cellular transport mechanisms.
• Pharmaceutical Development: Serves as a lead compound or a structural template for the synthesis of novel analogs with improved efficacy and pharmacokinetic profiles.
• Biochemical Assays: Used in high-throughput screening (HTS) platforms to identify new targets or modulators of microtubule function.
• Academic Research: Fundamental studies in cell biology, neurobiology (due to effects on neuronal microtubules), and developmental biology.

Basic Information

Product Name	Pironetin
CAS No.	151519-02-7
Molecular Formula	C₂₀H₃₀O₅
Molecular Weight	350.45 g/mol
Synonyms	Pironetin; (-)-Pironetin; L-156,602; Antibiotic L 156602; (4E,6S,8S,10S,12S,13R,14S,16S)-16-Ethyl-6,13,14-trihydroxy-5,7,9,11,13,15-hexamethyl-4-oxabicyclo[10.4.0]hexadeca-1(12),4,15-triene-2,8-dione
EINECS	Contact for details

Quality Control

Our Pironetin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.