Description

6-Maleimidocaproic Acid Hydrazide, Trifluoroacetic Acid is a heterobifunctional crosslinking reagent designed for the stable conjugation of biomolecules. This compound is critical for creating well-defined, site-specific bioconjugates used in advanced therapeutic and diagnostic platforms. It is primarily utilized by researchers and manufacturers in the biopharmaceutical, diagnostics, and life sciences sectors for applications such as antibody-drug conjugate (ADC) development and protein labeling.

Application

• Antibody-Drug Conjugate (ADC) Linker: A key reagent for covalently attaching cytotoxic payloads to monoclonal antibodies via stable amide bonds.
• Protein-Protein Conjugation: Enables the crosslinking of different proteins or peptides for the creation of bispecific constructs or fusion protein mimics.
• Surface Immobilization: Used to functionalize sensor chips, nanoparticles, or solid supports with biomolecules for biosensor and diagnostic assay development.
• Fluorescent Probe & Dye Labeling: Facilitates the site-specific attachment of fluorophores or other reporter molecules to proteins and antibodies.
• Polymer-Biomolecule Conjugation: Employed in PEGylation and the synthesis of polymer-drug conjugates to improve pharmacokinetic properties.
• Vaccine Development: Acts as a linker for coupling antigens to carrier proteins to enhance immunogenicity.

Basic Information

Item	Details
Product Name	6-Maleimidocaproic Acid Hydrazide, Trifluoroacetic Acid
CAS No.	151038-94-7
Molecular Formula	C11H15N3O4 • C2HF3O2
Molecular Weight	379.28 g/mol
Synonyms	6-Maleimidocaproic Acid Hydrazide TFA Salt; EMCH TFA; 6-Maleimidocaproic Hydrazide Trifluoroacetate; N-(6-Maleimidocaproyl)hydrazine Trifluoroacetic Acid Salt; 6-Maleimidohexanoic Acid Hydrazide TFA; Maleimidocaproyl Hydrazide TFA; MC Hydrazide TFA Salt; (6-Maleimidocaproyl)hydrazine Trifluoroacetate
EINECS	Contact for details

Quality Control

Our 6-Maleimidocaproic Acid Hydrazide, Trifluoroacetic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and production. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.