Description

Tyrphostin Ag 568 is a potent and selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. This compound is a valuable research tool for studying signal transduction pathways involved in cell proliferation, differentiation, and oncogenesis. It is primarily utilized by researchers and scientists in the fields of biochemistry, molecular biology, and oncology for in vitro and in vivo studies.

Application

• Biochemical Research: A key reagent for investigating EGFR-mediated signaling cascades and their role in cellular processes.
• Cancer Research: Used to study the effects of EGFR inhibition on tumor cell growth, survival, and metastasis in experimental models.
• Drug Discovery: Serves as a reference compound or lead structure in the development of novel tyrosine kinase inhibitors for therapeutic applications.
• Signal Transduction Studies: Employed to dissect and validate specific pathways in cell culture and animal models to understand disease mechanisms.
• Academic & Pharmaceutical R&D: Essential for basic scientific research and pre-clinical development stages within university and industrial laboratories.

Basic Information

Product Name	Tyrphostin Ag 568
CAS No.	151013-48-8
Molecular Formula	C16H12N2O3
Molecular Weight	280.28 g/mol
Synonyms	AG 568; Tyrphostin AG 568; 4-Hydroxy-3,5-dimethoxybenzylidene malononitrile; 2-[(3,5-Dimethoxy-4-hydroxyphenyl)methylene]propanedinitrile; 3,5-Dimethoxy-4-hydroxybenzylidenemalononitrile; EGFR Inhibitor AG 568; NSC 693646
EINECS	Contact for details

Quality Control

Our Tyrphostin Ag 568 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.