Description

Ethanone, 1-(6-Chloro-3-Pyridinyl)-2,2,2-Trifluoro- (9Ci) is a high-purity trifluoromethyl ketone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique reactivity imparted by the trifluoroacetyl group adjacent to a chloropyridine ring, enabling precise chemical transformations. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules for active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation insecticides and herbicides, leveraging the bioactivity of the chloronicotinyl and trifluoromethyl motifs.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology Probes: Utilized in academic and industrial research to create enzyme inhibitors or labeling agents due to its electrophilic ketone functionality.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	Ethanone, 1-(6-Chloro-3-Pyridinyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	150698-72-9
Molecular Formula	C8H3ClF3NO
Molecular Weight	221.56 g/mol
Synonyms	1-(6-Chloro-3-pyridinyl)-2,2,2-trifluoroethanone; 6-Chloro-3-pyridyl trifluoromethyl ketone; 2,2,2-Trifluoro-1-(6-chloropyridin-3-yl)ethanone; 6-Chloro-3-trifluoroacetylpyridine; 3-Acetyl-6-chloropyridine, 2,2,2-trifluoro-; 1-(6-Chloro-3-pyridyl)-2,2,2-trifluoroethanone; (6-Chloro-3-pyridinyl)trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(6-Chloro-3-Pyridinyl)-2,2,2-Trifluoro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards guarantees a reliable supply of this high-value intermediate for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.