Description

Benzenesulfonyl Chloride, 3-(1,4-Dihydro-8-Methoxy-4-Oxo-2-Quinazolinyl)-4-Ethoxy- (9Ci) is a specialized sulfonyl chloride derivative, a high-value synthetic intermediate designed for advanced pharmaceutical and fine chemical research. Its core value lies in its reactive sulfonyl chloride group, which enables efficient sulfonamide bond formation, a critical step in constructing complex molecules with targeted biological activity. This compound is essential for R&D chemists and process development scientists in the pharmaceutical industry, particularly those focused on developing novel quinazolinone-based therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinazolinone derivatives with potential pharmacological activity.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process chemistry for constructing the core scaffold of target molecules during drug discovery and development.
• Bioconjugation & Probe Synthesis: The reactive sulfonyl chloride moiety allows for the labeling or modification of biomolecules (e.g., proteins, peptides) for biochemical research and diagnostic applications.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and specialty materials with specific surface properties.
• Agrochemical Research: Intermediate in the exploratory synthesis of new agrochemical compounds, such as herbicides or plant growth regulators, leveraging the quinazolinone structure.

Basic Information

Product Name	Benzenesulfonyl Chloride, 3-(1,4-Dihydro-8-Methoxy-4-Oxo-2-Quinazolinyl)-4-Ethoxy- (9Ci)
CAS No.	150479-72-4
Molecular Formula	C18H17ClN2O5S
Molecular Weight	408.86 g/mol
Synonyms	4-Ethoxy-3-(8-methoxy-4-oxo-1,4-dihydro-2-quinazolinyl)benzenesulfonyl chloride; 3-(1,4-Dihydro-8-methoxy-4-oxo-2-quinazolinyl)-4-ethoxybenzenesulfonyl chloride; 150479-72-4; 4-Ethoxy-3-(8-methoxy-4-oxo-1,4-dihydroquinazolin-2-yl)benzenesulfonyl chloride; 2-(4-Ethoxy-3-sulfamoylphenyl)-8-methoxy-4H-quinazolin-4-one (precursor); 8-Methoxy-2-[4-ethoxy-3-(sulfonyl chloride)phenyl]-4(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our Benzenesulfonyl Chloride, 3-(1,4-Dihydro-8-Methoxy-4-Oxo-2-Quinazolinyl)-4-Ethoxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.