Description

L-N5-(1-Iminoethyl)Ornithine Hydrochloride is a high-purity, chemically defined compound primarily used as a selective and potent inhibitor of nitric oxide synthase (NOS). This specific activity makes it a critical research tool and a valuable intermediate in the development of therapeutic agents targeting nitric oxide pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors engaged in cardiovascular, neurological, and inflammatory disease research.

Application

• Biochemical Research: A key tool for studying the role of nitric oxide (NO) in cellular signaling, inflammation, and disease models.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel NOS inhibitors for potential drug development.
• Enzyme Inhibition Studies: Used in vitro and in vivo to specifically inhibit inducible NOS (iNOS) and neuronal NOS (nNOS) isoforms.
• Academic & Clinical Research: Supports fundamental and applied research in universities, hospitals, and contract research organizations (CROs).
• Reference Standard: Employed as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	L-N5-(1-Iminoethyl)Ornithine Hydrochloride
CAS No.	150403-88-6
Molecular Formula	C7H16N3O2•HCl
Molecular Weight	223.68 g/mol
Synonyms	L-NIO Hydrochloride; N5-(1-Iminoethyl)-L-ornithine hydrochloride; L-Nω-(1-Iminoethyl)ornithine hydrochloride; (S)-2,5-Diamino-N-(1-iminoethyl)pentanamide hydrochloride; NOS Inhibitor I; Nitric Oxide Synthase Inhibitor; Ornithine, N5-(1-iminoethyl)-, monohydrochloride, L-
EINECS	Contact for details

Quality Control

Our L-N5-(1-Iminoethyl)Ornithine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range available on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Chiral Purity	≥99.0% (L-isomer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.