Description

1,3-Difluoro-2-Iodo-5-(trans-4-Propylcyclohexyl)Benzene is a high-purity, multi-functional organic intermediate featuring a unique combination of fluorine, iodine, and a cyclohexyl substituent. This compound is valued for its role in advanced material synthesis and pharmaceutical research, where its specific substitution pattern enables precise molecular engineering. It is primarily sought after by R&D chemists and process development scientists in the fields of liquid crystal materials, organic electronics, and medicinal chemistry for constructing complex target molecules.

Application

• Liquid Crystal (LC) Material Synthesis: A key building block for creating advanced liquid crystal molecules, particularly for display technologies, due to its polarizable iodine atom and fluorinated benzene core which influence dielectric anisotropy and mesophase stability.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), where the iodine moiety allows for further functionalization via cross-coupling reactions.
• Organic Electronic Materials: Used in the development of organic semiconductors, hole-transport materials, and non-linear optical (NLO) materials, leveraging its electron-deficient aromatic system.
• Agrochemical Research: Employed as an intermediate in the design and synthesis of new generation herbicides and pesticides, where fluorinated compounds often exhibit enhanced bioactivity and stability.
• Ligand and Catalyst Development: The iodine and fluorine atoms make it a useful scaffold for developing specialized ligands in transition metal catalysis and organocatalysis.
• Chemical Research & Development: A versatile reagent for academic and industrial research focused on novel aromatic substitution chemistry and the study of steric and electronic effects.

Basic Information

Product Name	1,3-Difluoro-2-Iodo-5-(trans-4-Propylcyclohexyl)Benzene
CAS No.	149705-66-8
Molecular Formula	C15H19F2I
Molecular Weight	364.22 g/mol
Synonyms	5-(trans-4-Propylcyclohexyl)-1,3-difluoro-2-iodobenzene; 2-Iodo-1,3-difluoro-5-(trans-4-propylcyclohexyl)benzene; trans-4-(3,5-Difluoro-2-iodophenyl)propylcyclohexane; 1,3-Difluoro-2-iodo-5-(4-propylcyclohexyl)benzene (trans); Benzene, 1,3-difluoro-2-iodo-5-(4-propylcyclohexyl)-, trans-; 149705-66-8 (CAS Name Base); LC Intermediate 149705-66-8
EINECS	Contact for details

Quality Control

Our 1,3-Difluoro-2-Iodo-5-(trans-4-Propylcyclohexyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for sensitive synthesis and material science research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.