Description

3-Cyano-4-Dimethylamino-2-Fluorobenzaldehyde is a high-purity, multi-functional aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring cyano, dimethylamino, and fluoro substituents, makes it a versatile precursor for constructing complex heterocyclic systems and functional materials. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its fluorinated aromatic core contributes to biological activity and metabolic stability.
• Functional Material Precursor: Serves as a starting material for creating organic electronic materials, dyes, pigments, and photoactive compounds.
• Chemical Research & Development: Employed in academic and industrial labs for method development, library synthesis, and exploring new chemical reactions due to its reactive aldehyde and electron-donating/withdrawing groups.
• Ligand and Catalyst Development: Useful for constructing sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.

Basic Information

Product Name	3-Cyano-4-Dimethylamino-2-Fluorobenzaldehyde
CAS No.	148901-53-5
Molecular Formula	C10H9FN2O
Molecular Weight	192.19 g/mol
Synonyms	2-Fluoro-4-(dimethylamino)-3-formylbenzonitrile; 4-Dimethylamino-2-fluoro-3-cyanobenzaldehyde; 2-Fluoro-3-cyano-4-(dimethylamino)benzaldehyde; 3-Formyl-4-(N,N-dimethylamino)-2-fluorobenzonitrile; 148901-53-5; Benzonitrile, 2-fluoro-4-(dimethylamino)-3-formyl-; 4-(Dimethylamino)-2-fluoro-3-formylbenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Cyano-4-Dimethylamino-2-Fluorobenzaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.