Description

2-Benzyloxy-3-Fluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a benzyl-protected phenolic oxygen and an aldehyde group adjacent to a fluorine atom, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the influence of the fluorine atom on bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the benzyloxy-fluorobenzaldehyde scaffold can contribute to enhanced activity and selectivity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and fluorescent dyes, where the fluorine substitution can modify electronic properties and intermolecular interactions.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	2-Benzyloxy-3-Fluorobenzaldehyde
CAS No.	148872-79-1
Molecular Formula	C₁₄H₁₁FO₂
Molecular Weight	230.24 g/mol
Synonyms	3-Fluoro-2-(phenylmethoxy)benzaldehyde; 2-(Benzyloxy)-3-fluorobenzaldehyde; Benzaldehyde, 2-(benzyloxy)-3-fluoro-; 3-Fluoro-2-benzyloxybenzaldehyde; 2-Benzyloxy-3-fluorobenzenecarboxaldehyde; 148872-79-1; 3-Fluoro-2-(benzyloxy)benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Benzyloxy-3-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.