Description

2-Hydroxy-7-Fluoroquinoline is a high-purity, functionalized quinoline derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for applications in medicinal chemistry, ligand synthesis, and as a precursor for fluorescent dyes.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel fluoroquinolone-based antibiotics and other bioactive molecules targeting various therapeutic areas.
• Agrochemical Research: Used as a precursor in developing new generation pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Coordination Chemistry & Catalysis: Serves as a chelating ligand for transition metals, useful in creating catalysts for organic transformations and in materials science.
• Fluorescent Probe Development: The fluorinated quinoline structure is utilized in designing and synthesizing advanced fluorescent markers and sensors for biochemical assays.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as components for OLEDs (Organic Light-Emitting Diodes) or charge-transport materials.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	2-Hydroxy-7-Fluoroquinoline
CAS No.	148136-14-5
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	7-Fluoro-2-quinolinol; 7-Fluoroquinolin-2-ol; 2-Quinolinol, 7-fluoro-; 7-Fluoro-2-hydroxyquinoline; 2-Hydroxy-7-fluoroquinoline; 7-Fluoro-1-azanaphthalene-2-ol
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-7-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.