Description

1-(Glucopyranosyl)Pentobarbital is a specialized chemical conjugate that combines a pentobarbital moiety with a glucopyranosyl unit. This molecular architecture is significant for its potential to modify the pharmacokinetic profile and targeting of the parent barbiturate compound. It is primarily of interest to researchers and developers in the pharmaceutical and life sciences sectors for advanced drug discovery and biochemical studies.

Application

• Pharmaceutical Research: Serves as a key intermediate or reference standard in the development of novel barbiturate derivatives with modified activity.
• Metabolic Studies: Used in biochemical research to investigate the metabolism and conjugation pathways of barbiturates.
• Prodrug Development: Investigated for its potential as a prodrug candidate, where the sugar moiety may influence solubility, bioavailability, or targeted delivery.
• Analytical Reference Standard: Employed as a high-purity standard in analytical laboratories for method development and quality control (HPLC, LC-MS).
• Neuroscience Research: Utilized in studies exploring the structure-activity relationships of GABAA receptor modulators.

Basic Information

Product Name	1-(Glucopyranosyl)Pentobarbital
CAS No.	147839-07-4
Molecular Formula	C16H24N2O8
Molecular Weight	372.37 g/mol
Synonyms	Pentobarbital 1-glucoside; 5-Ethyl-5-(1-methylbutyl)-1-(β-D-glucopyranosyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 1-(β-D-Glucopyranosyl)-5-ethyl-5-(1-methylbutyl)barbituric acid; Glucopyranosyl pentobarbital; Pentobarbital glucoside; NSC 401005; 1-Glucosylpentobarbital
EINECS	Contact for details

Quality Control

Our 1-(Glucopyranosyl)Pentobarbital is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity assessment by chromatographic techniques (HPLC). We provide Certificates of Analysis (COA) with detailed specifications for research and development purposes, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.