Description

n-Fluoro-4,6-Bis(trifluoromethyl)pyridinium-2-sulfonate is a highly fluorinated pyridinium salt derivative, serving as a versatile and potent fluorinating reagent in advanced organic synthesis. Its value lies in its ability to introduce fluorine atoms or trifluoromethyl groups into complex molecular architectures, a critical transformation for modifying the physicochemical properties of target compounds. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination is key to developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the late-stage fluorination of drug candidates to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and pesticides where fluorinated motifs improve efficacy and environmental profile.
• Fluorinated Building Blocks: Serves as a precursor for generating other fluorinated synthons and complex organic molecules in medicinal and materials chemistry.
• Materials Science Research: Employed in the creation of fluorinated polymers, liquid crystals, and electronic materials with unique dielectric and surface properties.
• Radiochemistry & Tracer Synthesis: Potential use in the preparation of 18F-labeled compounds for Positron Emission Tomography (PET) imaging agents.
• Catalysis & Ligand Design: Can be utilized to synthesize fluorinated ligands for catalysis or as a component in specialty catalyst systems.

Basic Information

Product Name	n-Fluoro-4,6-Bis(trifluoromethyl)pyridinium-2-Sulfonate
CAS No.	147541-03-5
Molecular Formula	C8H2F7NO3S
Molecular Weight	325.16 g/mol
Synonyms	4,6-Bis(trifluoromethyl)-2-fluoropyridinium-1-sulfonate; 1-Fluoro-4,6-bis(trifluoromethyl)pyridinium-2-sulfonate; N-Fluoro-4,6-bis(trifluoromethyl)pyridinium sulfonate; F-BTP; NFBS; Fluoropyridinium Sulfonate Reagent
EINECS	Contact for details

Quality Control

Our n-Fluoro-4,6-Bis(trifluoromethyl)pyridinium-2-sulfonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.