Description

16,18-Ethano 20-Ethyl-6-Oxoprostaglandin E1 is a synthetic prostaglandin E1 (PGE1) analog, a high-purity advanced pharmaceutical intermediate designed for targeted therapeutic research and development. This compound is valued for its structural modifications, which enhance metabolic stability and receptor selectivity compared to native prostaglandins. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel cardiovascular, anti-inflammatory, and cytoprotective agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel prostaglandin-based therapeutics targeting vascular and inflammatory pathways.
• Cardiovascular Research: Used in preclinical studies to investigate vasodilation, platelet aggregation inhibition, and treatments for peripheral vascular diseases.
• Ophthalmic Drug Development: Serves as a precursor for potential treatments for glaucoma and ocular hypertension due to its intraocular pressure-lowering effects.
• Wound Healing & Tissue Repair: Applied in research focused on cytoprotection, angiogenesis, and accelerating the healing process in various tissue models.
• Biochemical Tool Compound: Employed in vitro and in vivo to study the specific roles and signaling mechanisms of EP receptor subtypes.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	16,18-Ethano 20-Ethyl-6-Oxoprostaglandin E1
CAS No.	147511-91-9
Molecular Formula	C24H38O5
Molecular Weight	406.56 g/mol
Synonyms	20-Ethyl-6-oxo-16,18-ethano-PGE1; 16,18-Ethano-20-ethyl-6-oxoprostaglandin E1; 6-Oxo-16,18-ethano-20-ethyl-PGE1; 20-Ethyl-6-keto-16,18-ethanoprostaglandin E1; Ethano Prostaglandin E1 Derivative; PGE1 Ethano Analog; Prostaglandin E1 Ethyl Ethano Analog; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our 16,18-Ethano 20-Ethyl-6-Oxoprostaglandin E1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.