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Aroxaprostol CAS NO 147335-23-7
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CAS No.:147335-23-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Aroxaprostol is a synthetic prostaglandin analog with significant biological activity. This compound is valued for its role as a key intermediate and active pharmaceutical ingredient (API) in advanced therapeutic research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on cardiovascular, ophthalmic, and inflammatory disease pathways. Our supply ensures high purity and consistent quality to support critical applications from preclinical studies to commercial manufacturing.
Application
- Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced prostaglandin-based therapeutics.
- Active Pharmaceutical Ingredient (API): Used in the formulation of ophthalmic solutions for conditions like glaucoma.
- Cardiovascular Research: Investigated for its effects on vasodilation and platelet aggregation in preclinical models.
- Inflammatory Mediator Studies: Employed in biochemical research to study prostaglandin receptors and signaling pathways.
- Reference Standard: Provides a high-purity standard for analytical method development and quality control in pharmaceutical labs.
- Veterinary Medicine: Potential applications in developing treatments for animal health conditions.
Basic Information
| Product Name | Aroxaprostol |
| CAS No. | 147335-23-7 |
| Molecular Formula | C₂₃H₃₈O₅ |
| Molecular Weight | 394.55 g/mol |
| Synonyms | 9-Oxo-11α,15S-dihydroxy-17S,20-dimethyl-prosta-5Z,13E-dien-1-oic acid; 17,20-Dimethyl PGE₂; Aroxaprostolum; UNII-7D8K6687QO; 9-Keto-11α,15α-dihydroxy-17α,20-dimethyl-prosta-5-cis,13-trans-dienoic acid; 17(S),20-Dimethyl-prostaglandin E2 |
| EINECS | Contact for details |
Quality Control
Every batch of Aroxaprostol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and potency meet stringent specifications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all test results. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for API manufacturing.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single impurity ≤ 0.5% |
| Water Content (KF) | ≤ 1.0% w/w |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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