Description

2-Hydroxyaldosterone is a key hydroxylated metabolite of the primary mineralocorticoid hormone, aldosterone. This compound is of significant interest in biochemical research and pharmaceutical development for its role in the renin-angiotensin-aldosterone system (RAAS). It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in metabolic studies, hypertension research, and the development of novel analytical standards.

Application

• Biochemical Research Standard: Serves as a critical reference standard for the study of aldosterone metabolism and steroid hormone pathways.
• Diagnostic Assay Development: Used in the development and calibration of immunoassays and LC-MS/MS methods for precise hormone level quantification in clinical samples.
• Pharmaceutical R&D: Employed in metabolic and pharmacokinetic studies for drugs targeting hypertension, heart failure, and renal diseases.
• Endocrinology Studies: A vital tool for investigating disorders related to mineralocorticoid activity, such as Conn's syndrome and other forms of hyperaldosteronism.
• Academic Research: Used in university and institutional labs for fundamental research into steroidogenesis and hormone regulation.

Basic Information

Product Name	2-Hydroxyaldosterone
CAS No.	147199-27-7
Molecular Formula	C21H28O6
Molecular Weight	376.45 g/mol
Synonyms	2-Hydroxyaldosterone; 18,11-Hemiacetal of 11β,21-dihydroxy-2,20-dioxopregn-4-en-18-al; 2-Oxoaldosterone; Aldosterone 2-hydroxy derivative; 11β,21-Dihydroxy-2,20-dioxopregn-4-en-18-al 18,11-hemiacetal
EINECS	Contact for details

Quality Control

Our 2-Hydroxyaldosterone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or CoA. Desiccate if necessary for long-term storage. Handle with appropriate personal protective equipment in a well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.