Description

Carbamic Acid, n-(Chlorosulfonyl)-, 1,1-Dimethylethyl Ester is a specialized organic sulfonyl chloride derivative, serving as a critical building block in advanced synthetic chemistry. Its primary value lies in its dual functionality, acting as a protected carbamate and a reactive sulfonyl chloride, enabling the controlled introduction of sulfonamide groups. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of sulfonamide-based drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with sulfonamide moieties.
• Peptide Chemistry: Used in the preparation of sulfonylated amino acid derivatives and protected peptide fragments.
• Material Science Research: Intermediate in the development of specialty polymers and functional materials requiring sulfonamide linkages.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and molecular tags for studying enzyme function.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of client-specific target molecules in multistep syntheses.

Basic Information

Product Name	Carbamic Acid, n-(Chlorosulfonyl)-, 1,1-Dimethylethyl Ester
CAS No.	147000-89-3
Molecular Formula	C5H10ClNO4S
Molecular Weight	215.66 g/mol
Synonyms	tert-Butyl N-(Chlorosulfonyl)carbamate; tert-Butyl (Chlorosulfonyl)carbamate; N-(tert-Butoxycarbonyl)sulfamoyl Chloride; BOC-Sulfamoyl Chloride; (tert-Butoxycarbonyl)sulfamoyl Chloride; 1,1-Dimethylethyl N-(Chlorosulfonyl)carbamate; Carbamic Acid, (Chlorosulfonyl)-, 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-(Chlorosulfonyl)-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.