Description

Sodium-Nucleoside Cotransporter CAS NO 146888-66-6 is a specialized biochemical compound designed to facilitate the co-transport of sodium ions and nucleosides across cellular membranes. This mechanism is critical for regulating intracellular nucleoside concentrations, which directly impacts nucleic acid synthesis and cellular metabolism. It is therefore an essential research tool for scientists in pharmacology, molecular biology, and oncology studying nucleoside uptake, drug resistance, and the development of targeted therapeutics.

Application

• Pharmacological Research: Used as a reference standard or inhibitor in studies investigating nucleoside transporter function and kinetics.
• Drug Discovery & Development: Serves as a key tool for screening and evaluating potential chemotherapeutic agents that target nucleoside uptake pathways in cancer cells.
• Molecular Biology Studies: Employed in experiments to understand the regulation of nucleoside salvage pathways and their role in cell proliferation and survival.
• Biochemical Assay Development: Utilized as a critical component in developing high-throughput assays for transporter activity and inhibitor potency.
• Academic Research: Supports fundamental research in cellular physiology, membrane transport mechanisms, and nucleotide metabolism.

Basic Information

Product Name	Sodium-Nucleoside Cotransporter
CAS No.	146888-66-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sodium-coupled nucleoside transporter; Nucleoside sodium symporter; hCNT inhibitor (context-dependent); Sodium/nucleoside cotransporter protein; SLC28 transporter family ligand; Nucleoside transport inhibitor 146888-66-6
EINECS	Contact for details

Quality Control

Our Sodium-Nucleoside Cotransporter is produced under stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including purity verification by HPLC and structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and assay results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Allow the product to equilibrate to room temperature in a dry environment before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0%
Solubility	Soluble in DMSO, sparingly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.