Description

Noc-18 CAS NO 146724-94-9 is a high-purity, synthetic chemical compound widely recognized as a potent and selective nitric oxide (NO) donor. Its ability to release nitric oxide in a controlled manner makes it a critical research tool for studying cellular signaling pathways, vasodilation, and neurotransmission. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors, particularly for applications in cardiovascular research, neuroscience, and drug discovery.

Application

• Biochemical Research: A fundamental tool for studying the physiological and pathological roles of nitric oxide in cellular models.
• Pharmaceutical R&D: Used in the development and screening of novel therapeutics targeting NO-related pathways, such as for hypertension and erectile dysfunction.
• Neuroscience Studies: Employed to investigate the function of NO as a neurotransmitter and neuromodulator in the central and peripheral nervous systems.
• Cardiovascular Research: Applied in studies of vasodilation, blood pressure regulation, and endothelial function.
• Cell Signaling Pathways: Utilized to activate soluble guanylyl cyclase (sGC) and study downstream cGMP-mediated effects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratory settings.

Basic Information

Product Name	Noc-18
CAS No.	146724-94-9
Molecular Formula	C12H16N6O4
Molecular Weight	308.30 g/mol
Synonyms	NOC-18; DETA NONOate; Diethylenetriamine NONOate; (Z)-1-[N-(2-Aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate; DPTA NONOate; 1,1-Diethyl-2-hydroxy-2-nitrosohydrazine Sodium Salt (related compound); DETA/NO; Diazen-1-ium-1,2-diolate, 1-[2-(2-aminoethyl)amino]ethyl]amino]-
EINECS	Contact for details

Quality Control

Our Noc-18 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, water content, and residual solvents to meet your specific research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Nitric Oxide Release	Confirmed by standard assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.