Description

4-Chloro-2,5-Dimethylphenylsulfonyl Chloride is a key sulfonyl chloride derivative, serving as a versatile and reactive building block in advanced organic synthesis. Its structure makes it particularly valuable for introducing the 4-chloro-2,5-dimethylphenylsulfonyl moiety into target molecules, enabling the creation of compounds with specific functionalities. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where the sulfonyl group is a key pharmacophore.
• Dyestuff and Pigment Manufacturing: Acts as a precursor in the creation of specialized dyes and pigments, contributing to color fastness and specific properties.
• Polymer Modification: Employed to introduce functional sulfonyl groups into polymer chains, altering material characteristics like solubility or reactivity.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Ligand and Catalyst Preparation: Used in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	4-Chloro-2,5-Dimethylphenylsulfonyl Chloride
CAS No.	145980-63-8
Molecular Formula	C8H8Cl2O2S
Molecular Weight	239.12 g/mol
Synonyms	2,5-Dimethyl-4-chlorobenzenesulfonyl chloride; 1-Chloro-4-sulfonyl chloride-2,5-dimethylbenzene; 4-Chloro-2,5-dimethylbenzenesulfonyl chloride; 4-Chloro-2,5-xylenesulfonyl chloride; (4-Chloro-2,5-dimethylphenyl)sulfonyl chloride; 2,5-Dimethyl-4-chlorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,5-Dimethylphenylsulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.