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1H-Pyrrolo[2,3-B]Pyridine,5-Fluoro-2-Methyl-(9Ci) CAS NO 145934-92-5
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CAS No.:145934-92-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1H-Pyrrolo[2,3-B]Pyridine,5-Fluoro-2-Methyl-(9Ci) is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery. Pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers need this precise chemical scaffold to construct complex molecules with targeted biological activity.
Application
- Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small-molecule therapeutics.
- Agrochemical Research: Used in developing new generation herbicides and fungicides with enhanced efficacy.
- Material Science: Serves as a precursor for organic electronic materials and functional dyes.
- Chemical Biology: Employed as a probe or tag in medicinal chemistry and biochemical studies.
- Academic & Contract Research: Essential for novel heterocyclic chemistry research in university and CRO laboratories.
- Custom Synthesis: A starting material for the contract manufacturing of bespoke fine chemicals.
Basic Information
| Product Name | 1H-Pyrrolo[2,3-B]Pyridine,5-Fluoro-2-Methyl-(9Ci) |
| CAS No. | 145934-92-5 |
| Molecular Formula | C8H7FN2 |
| Molecular Weight | 150.16 g/mol |
| Synonyms | 5-Fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-2-methyl-7-azaindole; 2-Methyl-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridine (9CI); 5-Fluoro-2-methyl-7-aza-indole; 1H-Pyrrolo[2,3-b]pyridine, 5-fluoro-2-methyl-; 145934-92-5; 5-Fluoro-2-methyl-7-azaindole |
| EINECS | Contact for details |
Quality Control
Our 1H-Pyrrolo[2,3-B]Pyridine,5-Fluoro-2-Methyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Trusted Manufacturer
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Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






