Description

15(S)-Latanoprost is a high-purity, stereochemically defined prostaglandin F2α analog. This compound is a critical chiral intermediate and reference standard in the research and development of ophthalmic pharmaceuticals. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories focused on glaucoma therapeutics. The product is supplied to meet the stringent requirements of advanced pharmaceutical synthesis and quality control.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of latanoprost API and related prostaglandin analogs.
• Reference Standard: Used in analytical method development, validation, and quality control (QC/QA) testing for ophthalmic drug products.
• Research & Development: Critical for preclinical studies, metabolic pathway investigation, and the development of novel drug delivery systems for glaucoma.
• Process Chemistry: Serves as a benchmark in optimizing stereoselective synthesis routes and scaling up production processes.
• Regulatory Submissions: Provides essential data and materials for drug master files (DMF), investigational new drug (IND) applications, and new drug applications (NDA).

Basic Information

Product Name	15(S)-Latanoprost
CAS No.	145773-22-4
Molecular Formula	C26H40O5
Molecular Weight	432.60 g/mol
Synonyms	15(S)-Latanoprost; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-dien-1-oic acid isopropyl ester; Latanoprost Impurity C; 15-Epilatanoprost; Latanoprost 15(S)-Epimer; 15(S)-Hydroxy Latanoprost; UNII-6Z5B6HVF6O
EINECS	Contact for details

Quality Control

Our 15(S)-Latanoprost is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and impurity profile analysis by HPLC, to ensure it meets exacting standards for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and compliance with specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. For long-term storage, keep desiccated to protect from moisture. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (15(S)-isomer)
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.