Description

5-Chloro-2-(Difluoromethoxy)Benzaldehyde is a versatile and high-value aromatic aldehyde building block, distinguished by its unique difluoromethoxy and chloro substituents. This compound is critical for synthesizing advanced pharmaceutical intermediates and agrochemicals, where its specific substitution pattern enables precise molecular design. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the difluoromethoxy group for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: A valuable reagent in cross-coupling reactions and as a substrate for developing new synthetic methodologies in academic and industrial research.
• Flavor & Fragrance Industry: Potential intermediate for creating complex, fluorinated aromatic molecules used in high-value fragrance compounds.

Basic Information

Product Name	5-Chloro-2-(Difluoromethoxy)Benzaldehyde
CAS No.	145742-68-3
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	5-Chloro-2-(difluoromethoxy)benzaldehyde; 2-(Difluoromethoxy)-5-chlorobenzaldehyde; Benzaldehyde, 5-chloro-2-(difluoromethoxy)-; 5-Chloro-α,α-difluoroanisaldehyde; 145742-68-3 (CAS); 5-Chloro-2-OCHF2-benzaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Difluoromethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.