Description

Hexakis(2,3,6-Tri-o-Ethyl)-α-Cyclodextrin is a synthetically modified derivative of α-cyclodextrin, where all primary and secondary hydroxyl groups are ethylated, creating a lipophilic cavity with unique host-guest complexation properties. This chemical modification significantly enhances its solubility in organic solvents and its ability to encapsulate non-polar molecules, making it a powerful tool for molecular recognition and separation. It is a critical material for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require advanced chiral separation, catalysis, or controlled release systems. The compound is supplied under strict quality control to ensure batch-to-batch consistency for demanding R&D and production applications.

Application

• Chiral Resolution Agent: Used in HPLC and capillary electrophoresis for the separation of enantiomers in pharmaceutical intermediates and active ingredients.
• Catalyst and Reaction Modifier: Acts as a phase-transfer catalyst or host in supramolecular chemistry to enhance reaction rates and selectivities.
• Drug Delivery & Formulation: Serves as a solubilizing and stabilizing agent for poorly water-soluble drugs in pre-formulation studies.
• Chemical Sensor Development: Employed as a selective binding site in the design of fluorescent or electrochemical sensors for specific analytes.
• Environmental Analysis: Utilized in sample preparation and extraction techniques for the detection of organic pollutants.
• Fragrance & Flavor Stabilization: Helps to encapsulate and control the release of volatile aromatic compounds.
• Material Science: Incorporated into polymers and coatings to create functional materials with specific molecular recognition properties.
• Reference Standard: Provides a high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Item	Details
Product Name	Hexakis(2,3,6-Tri-o-Ethyl)-α-Cyclodextrin
CAS No.	145454-97-3
Molecular Formula	C60H108O30
Molecular Weight	1333.5 g/mol
Synonyms	Per-2,3,6-tri-O-ethyl-α-cyclodextrin; α-Cyclodextrin, 2,3,6-tri-O-ethyl-; Hexakis(2,3,6-tri-O-ethyl)-α-cyclodextrin; Ethylated α-cyclodextrin; TE-α-CD; 2,3,6-Tri-O-ethyl-α-cyclodextrin; Fully ethylated α-cyclodextrin; E-α-CD
EINECS	Contact for details

Quality Control

Every batch of our Hexakis(2,3,6-Tri-o-Ethyl)-α-Cyclodextrin is manufactured and tested under a rigorous quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity requirements for research and industrial use. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support compliance with cGMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent moisture uptake and potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Solubility	Freely soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.