Description

13,14-Dehydro-15-Cyclohexyl Carbaprostacyclin is a chemically stable carbacyclin analog, a potent and selective agonist for the IP (prostacyclin) receptor. This compound is valued for its significant role in cardiovascular and pulmonary research, offering a stable tool for studying prostacyclin-mediated pathways. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on developing novel therapeutics for hypertension, thrombosis, and pulmonary arterial hypertension.

Application

• Pharmaceutical Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel cardiovascular and pulmonary therapeutics.
• Biochemical Research: Used as a potent and selective pharmacological tool to study IP receptor signaling, vasodilation, and platelet aggregation inhibition in vitro and in vivo.
• Preclinical Studies: Employed in animal models to investigate the efficacy and mechanisms of action for potential drugs targeting pulmonary arterial hypertension (PAH) and related disorders.
• Chemical Synthesis: Serves as a sophisticated synthetic intermediate for the preparation of more complex prostacyclin analogs and labeled compounds for tracer studies.
• Cell Signaling Pathways: Utilized in cell-based assays to elucidate the role of the prostacyclin pathway in vascular smooth muscle relaxation and cytoprotection.

Basic Information

Product Name	13,14-Dehydro-15-Cyclohexyl Carbaprostacyclin
CAS No.	145375-81-1
Molecular Formula	C24H38O4
Molecular Weight	390.56 g/mol
Synonyms	15-Cyclohexyl-13,14-didehydro-16,17,18,19,20-pentanor-9-deoxy-9α,11α-epoxycarbaprostaglandin I2; 15-Cyclohexyl-13,14-didehydro-16,17,18,19,20-pentanor-9-deoxy-9α,11α-epoxycarbacyclin; 15-Cyclohexylcarbacyclin; Carbaprostacyclin analog; 15-Cyclohexyl-13,14-didehydrocarbacyclin; IP receptor agonist; CAS 145375-81-1
EINECS	Contact for details

Quality Control

Our 13,14-Dehydro-15-Cyclohexyl Carbaprostacyclin is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.