Description

Tegaserod is a selective serotonin 5-HT4 receptor partial agonist, a pharmaceutical active ingredient with significant therapeutic applications. This compound is valued for its targeted mechanism of action, offering a specific pharmacological profile for drug development and manufacturing. It is primarily required by pharmaceutical companies and research institutions engaged in the development of treatments for gastrointestinal motility disorders.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of prescription medications.
• Gastrointestinal Motility Research: Critical tool for in vitro and in vivo studies targeting 5-HT4 receptor pathways.
• Drug Development: Used in preclinical and clinical development stages for new therapeutic entities.
• Reference Standard: Serves as a high-purity standard for analytical testing, quality control, and regulatory submissions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for finished dosage form production.
• Academic Research: Utilized in university and institutional labs for pharmacological and biochemical studies.

Basic Information

Product Name	Tegaserod
CAS No.	145158-71-0
Molecular Formula	C16H23N5O
Molecular Weight	301.39 g/mol
Synonyms	Tegaserod Maleate; SDZ HTF 919; HTF 919; Zelnorm; Zelmac; 3-(5-Methoxy-1H-indol-3-ylmethylene)-N-pentylcarbazimidamide; 2-[(5-Methoxy-1H-indol-3-yl)methylene]-N-pentylhydrazinecarboximidamide
EINECS	Contact for details

Quality Control

Our Tegaserod is manufactured under strict quality systems to ensure it meets the rigorous standards required for pharmaceutical use. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines, and our quality commitment extends to supporting regulatory filings with consistent, reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.