Description

Piperazine, 1-[Bis(4-Fluorophenyl)Methyl]-4-[(3-Phenyl-2-Oxiranyl)Methyl]- is a specialized, high-value piperazine derivative with a complex molecular architecture, making it a critical intermediate in advanced organic synthesis. Its structure, featuring fluorinated aromatic rings and an oxiranyl (epoxide) moiety, is engineered to serve as a key building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Chemical Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular scaffolds, leveraging its reactive epoxide and piperazine functional groups.
• Agrochemical Research: Acts as an intermediate in the development of new-generation pesticides and herbicides, where the fluorinated aromatic system can enhance biological activity and stability.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or ligands for catalysts, utilizing its rigid, multi-aryl structure.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.

Basic Information

Product Name	Piperazine, 1-[Bis(4-Fluorophenyl)Methyl]-4-[(3-Phenyl-2-Oxiranyl)Methyl]-
CAS No.	144917-53-3
Molecular Formula	C26H26F2N2O
Molecular Weight	420.50 g/mol
Synonyms	1-[(4,4'-Difluorobenzhydryl)]-4-[(3-phenyloxiran-2-yl)methyl]piperazine; 4-[(3-Phenyloxiran-2-yl)methyl]-1-[bis(4-fluorophenyl)methyl]piperazine; 1-(Bis(4-fluorophenyl)methyl)-4-((3-phenyloxiran-2-yl)methyl)piperazine; 144917-53-3; 1-[Bis(4-fluorophenyl)methyl]-4-[(3-phenyl-2-oxiranyl)methyl]piperazine; 1-[(4-Fluorophenyl)(4-fluorophenyl)methyl]-4-[(3-phenyloxiran-2-yl)methyl]piperazine
EINECS	Contact for details

Quality Control

Every batch of Piperazine, 1-[Bis(4-Fluorophenyl)Methyl]-4-[(3-Phenyl-2-Oxiranyl)Methyl]- is produced and controlled under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods. Our quality commitment ensures material consistency and traceability, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.