Description

3-Pivaloylepinephrine is a chemically modified derivative of the endogenous catecholamine, epinephrine. This compound is of significant interest in pharmaceutical research and development, particularly for its potential as a prodrug or as a synthetic intermediate. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel adrenergic agents, prodrug strategies, and advanced chemical synthesis. The compound, identified by CAS NO 144750-97-0, offers a valuable tool for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel adrenergic receptor agonists or antagonists.
• Prodrug Development: Investigated for use in prodrug formulations designed to improve the stability, bioavailability, or targeted delivery of epinephrine-like compounds.
• Biochemical Research: Used as a reference standard or tool compound in studies of catecholamine metabolism, signal transduction, and enzyme kinetics.
• Chemical Synthesis: Employed in organic synthesis for the preparation of more complex molecules with potential therapeutic applications.
• Analytical Standard: Utilized as a high-purity standard for method development and quality control in analytical laboratories (e.g., HPLC, LC-MS).

Basic Information

Product Name	3-Pivaloylepinephrine
CAS No.	144750-97-0
Molecular Formula	C₁₄H₁₉NO₄
Molecular Weight	265.31 g/mol
Synonyms	3-Pivaloyl Epinephrine; 3-Pivaloyl Adrenaline; 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol 1-pivalate; 1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, 1-(2,2-dimethylpropanoate); Adrenaline 3-pivalate; Epinephrine 3-pivalate ester; Norepinephrine derivative pivalate
EINECS	Contact for details

Quality Control

Our 3-Pivaloylepinephrine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and other critical parameters as determined by HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.