Description

(3α,7α,17α)-7-Methyl-19-Norpregn-5(10)-En-20-Yne-3,17-Diol 3-(Hydrogen Sulfate) is a high-purity synthetic steroid derivative, specifically a sulfated norpregnene. This compound is a critical advanced pharmaceutical intermediate valued for its role in the synthesis of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of steroidal drugs and hormone-related therapies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in studies involving steroid hormone pathways and receptor interactions.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs targeting endocrine disorders and metabolic diseases.
• Process Development: Employed in the scale-up and optimization of synthetic routes for complex steroid molecules.

Basic Information

Product Name	(3α,7α,17α)-7-Methyl-19-Norpregn-5(10)-En-20-Yne-3,17-Diol 3-(Hydrogen Sulfate)
CAS No.	144466-06-8
Molecular Formula	C21H30O6S
Molecular Weight	410.53 g/mol
Synonyms	7α-Methyl-19-norpregn-5(10)-en-20-yne-3β,17β-diol 3-sulfate; 7-Methyl-19-norpregn-5(10)-en-20-yne-3,17-diol 3-(hydrogen sulfate); Tibolone 3-sulfate; 7α-Methyl-19-nortestosterone 3-sulfate derivative; Org OD-14 3-sulfate; Livial intermediate sulfate; Steroid sulfate intermediate CAS 144466-06-8
EINECS	Contact for details

Quality Control

Our (3α,7α,17α)-7-Methyl-19-Norpregn-5(10)-En-20-Yne-3,17-Diol 3-(Hydrogen Sulfate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.