Description

Pyrrolostatin CAS NO 144314-68-1 is a potent and specific inhibitor of the enzyme dipeptidyl peptidase IV (DPP-IV). This compound matters for its role in biochemical research and drug discovery, particularly in the study of metabolic disorders and immune regulation. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing novel therapeutics for diabetes and related conditions.

Application

• Biochemical Research: Used as a selective DPP-IV inhibitor to study enzyme kinetics, signaling pathways, and cellular processes in vitro.
• Drug Discovery & Development: Serves as a key pharmacological tool and reference standard in screening assays and lead optimization for metabolic disease targets.
• Academic Studies: Employed in university and institutional labs to investigate the role of DPP-IV in immunology, endocrinology, and cancer biology.
• Pharmaceutical Intermediates: Can be utilized in the synthesis of more complex molecules or prodrugs targeting DPP-IV activity.
• Diagnostic Development: Acts as a component in developing enzymatic assays and diagnostic kits for research purposes.

Basic Information

Product Name	Pyrrolostatin
CAS No.	144314-68-1
Molecular Formula	C₁₉H₂₀N₄O₃
Molecular Weight	352.39 g/mol
Synonyms	Pyrrolostatin; (2S)-1-[(2S,3S)-2-[(2S)-2-Cyanopyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]pyrrolidine-2-carbonitrile; DPP-IV Inhibitor II; NVP-DPP728 analogue; 1-[[(2S,3S)-2-[(2S)-2-Cyanopyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]](2S)-2-pyrrolidinecarbonitrile
EINECS	Contact for details

Quality Control

Our Pyrrolostatin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.