Description

2-Bromo-6-Fluoropyridine is a versatile halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its dual reactive sites, enabling selective functionalization to create complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for bioactivity.
• Ligand and Catalyst Development: Used to synthesize complex nitrogen-containing ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Intermediate in the creation of functionalized polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nucleophilic Aromatic Substitution: The bromine and fluorine atoms provide excellent leaving groups for selective substitution reactions.

Basic Information

Product Name	2-Bromo-6-Fluoropyridine
CAS No.	144100-07-2
Molecular Formula	C5H3BrFN
Molecular Weight	175.99 g/mol
Synonyms	6-Fluoro-2-bromopyridine; 2-Bromo-6-fluoropyridine; 6-Fluoro-2-bromopyridine; 2-Bromo-6-fluoro-pyridine; Pyridine, 2-bromo-6-fluoro-; 144100-07-2; 2-Br-6-F-Py
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluoropyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support custom purity requirements for specific R&D or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.