Description

4'-Acetyl-Biphenyl-4-Sulfonyl Chloride is a specialized organic intermediate featuring both acetyl and sulfonyl chloride functional groups on a biphenyl scaffold. This compound matters as a versatile building block for synthesizing more complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating sulfonamide derivatives and other functionalized aromatic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing sulfonamide moieties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the creation of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex organic dyes and functional pigments.
• Liquid Crystal Synthesis: A potential intermediate in the production of biphenyl-based liquid crystal compounds for display technologies.

Basic Information

Product Name	4'-Acetyl-Biphenyl-4-Sulfonyl Chloride
CAS No.	144006-69-9
Molecular Formula	C14H11ClO3S
Molecular Weight	294.75 g/mol
Synonyms	1-[4'-(Chlorosulfonyl)[1,1'-biphenyl]-4-yl]ethan-1-one; 4-Acetylbiphenyl-4'-sulfonyl chloride; [1,1'-Biphenyl]-4-acetyl-4'-sulfonyl chloride; 4'-Acetyl-4-biphenylsulfonyl chloride; p-Acetylbiphenyl-4'-sulfonyl chloride; (4'-Acetylbiphenyl-4-yl)sulfonyl chloride; 4-Acetyl-4'-sulfonylchlorobiphenyl
EINECS	Contact for details

Quality Control

Our 4'-Acetyl-Biphenyl-4-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its reactivity as a sulfonyl chloride and sensitivity to moisture, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.