Description

1-Fluoronaphthalene-2-Carbaldehyde is a high-purity fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a formyl group on the naphthalene ring system, makes it a versatile precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis, including those for cross-coupling reactions and asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and polymers for electronic and optoelectronic applications.
• Chemical Biology Probes: Acts as a starting material for creating fluorescent tags and molecular probes used in biochemical assays and diagnostic research.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, exploring new fluorination and functionalization reactions.

Basic Information

Product Name	1-Fluoronaphthalene-2-Carbaldehyde
CAS No.	143901-96-6
Molecular Formula	C₁₁H₇FO
Molecular Weight	174.17 g/mol
Synonyms	2-Formyl-1-fluoronaphthalene; 1-Fluoro-2-naphthaldehyde; 1-Fluoro-2-naphthalenecarboxaldehyde; 1-Fluoronaphthalene-2-carboxaldehyde; 1-Fluoro-2-formylnaphthalene; 2-Fluoronaphthalene-1-carbaldehyde (isomer); 1-Fluoro-β-naphthaldehyde; NSC 405124
EINECS	Contact for details

Quality Control

Our 1-Fluoronaphthalene-2-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity determination, NMR for structural confirmation, and GC-MS for impurity profiling. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent oxidation. Keep away from strong acids/bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.