Description

α-Amanitinylazobenzoylglycylglycine is a sophisticated synthetic peptide derivative designed for advanced biochemical research. This compound is of significant interest for its utility as a specialized tool in molecular biology and toxicology studies. It is primarily required by research institutions and pharmaceutical development laboratories focusing on enzyme inhibition, probe development, and the study of complex biological mechanisms.

Application

• Biochemical Research Probe: Used as a high-affinity, photoactivatable probe for studying RNA polymerase II inhibition and related transcriptional processes.
• Toxicology Studies: Serves as a reference standard or active component in research investigating the mechanisms of amatoxin poisoning and cellular apoptosis.
• Enzyme Inhibition Assays: Employed in in vitro assays to screen for or characterize inhibitors of specific enzymatic pathways.
• Molecular Biology Tool: Utilized in the development of novel experimental methodologies for labeling and tracking specific biomolecular interactions.
• Pharmaceutical R&D: Acts as a key intermediate or model compound in the discovery and development of novel therapeutic agents targeting transcription.

Basic Information

Product Name	α-Amanitinylazobenzoylglycylglycine
CAS No.	143873-65-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	α-Amanitinylazobenzoylglycylglycine; Amanitin-azobenzoyl-Gly-Gly; Azobenzoyl-Gly-Gly-α-amanitin; Photoactivatable α-amanitin derivative; Transcription inhibitor probe; Amatoxin-azobenzene conjugate
EINECS	Contact for details

Quality Control

Our α-Amanitinylazobenzoylglycylglycine is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term stability, consider storage at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	Solid (color to be specified per lot)
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Research Grade)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.