Description

n-Benzyloxycarbonyl-Leucyl-Leucyl-Phenylalaninal is a synthetic tripeptide aldehyde derivative, specifically designed as a potent and selective inhibitor of proteolytic enzymes. This compound matters for its critical role in biochemical research and pharmaceutical development, particularly in the study of protease mechanisms and the development of therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and biotechnology companies focused on enzymology, drug discovery, and the development of treatments for conditions involving dysregulated proteolysis.

Application

• Protease Inhibition Research: Serves as a key biochemical tool for studying the activity, specificity, and inhibition kinetics of various proteases, including calpains and cathepsins.
• Pharmaceutical Development: Used as a lead compound or intermediate in the discovery and synthesis of novel therapeutic agents targeting protease-related diseases.
• Biochemical Assay Standard: Employed as a reference standard in enzymatic assays to validate experimental models and screen for new inhibitor candidates.
• Cell Biology Studies: Applied in cellular models to investigate the role of specific proteases in signaling pathways, apoptosis, and other physiological processes.
• Academic Research: Utilized in university and institutional labs for fundamental research in biochemistry, medicinal chemistry, and molecular biology.

Basic Information

Product Name	n-Benzyloxycarbonyl-Leucyl-Leucyl-Phenylalaninal
CAS No.	143839-79-6
Molecular Formula	C30H41N3O5
Molecular Weight	523.67 g/mol
Synonyms	Z-Leu-Leu-Phe-H; Cbz-Leu-Leu-Phe-al; Benzyloxycarbonyl-Leu-Leu-Phe-al; Calpain Inhibitor III; MDL 28170; Z-LLF-H; N-Carbobenzoxy-L-leucyl-L-leucyl-L-phenylalaninal; Protease Inhibitor III
EINECS	Contact for details

Quality Control

Our n-Benzyloxycarbonyl-Leucyl-Leucyl-Phenylalaninal is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. Due to its hygroscopic and moisture-sensitive nature, the container should be allowed to reach room temperature before opening to prevent condensation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.