Description

1-Methoxy-9Alpha, 11Alpha, 15S-Trihydroxyprosta-5Z, 13E-Diene is a high-purity, synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound matters for its critical role in the synthesis of novel therapeutic agents targeting specific biological pathways. Pharmaceutical researchers and fine chemical manufacturers need this precise intermediate for developing new drugs in areas such as ophthalmology, cardiovascular health, and inflammation control.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Research: Used in the development of next-generation treatments for glaucoma and ocular hypertension.
• Cardiovascular Research: Serves as a precursor in studies targeting vasodilation and platelet aggregation.
• Inflammation & Immunology Studies: Employed in the creation of experimental compounds for modulating inflammatory responses.
• Biochemical Standard: Acts as a reference standard in analytical laboratories for method development and quality control.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, biologically active molecules.

Basic Information

Product Name	1-Methoxy-9Alpha, 11Alpha, 15S-Trihydroxyprosta-5Z, 13E-Diene
CAS No.	143656-18-2
Molecular Formula	C21H36O5
Molecular Weight	368.51 g/mol
Synonyms	9α,11α,15S-Trihydroxy-1-methoxyprosta-5Z,13E-dien-1-oic Acid; 1-Methoxy PGF2α Analogue; Prostaglandin F2α 1-Methyl Ether; 1-Methoxy Prostaglandin F2α; 1-O-Methyl Prostaglandin F2α; 1-MeO-PGF2α; CAS 143656-18-2
EINECS	Contact for details

Quality Control

Our 1-Methoxy-9Alpha, 11Alpha, 15S-Trihydroxyprosta-5Z, 13E-Diene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive and should be handled under controlled conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.