Description

Pyridine, 2-Fluoro-6-(1-Propynyl)- (9Ci) is a specialized fluorinated pyridine derivative that serves as a high-value building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a propynyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine moiety for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	Pyridine, 2-Fluoro-6-(1-Propynyl)- (9Ci)
CAS No.	143651-24-5
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	2-Fluoro-6-(prop-1-yn-1-yl)pyridine; 2-Fluoro-6-prop-1-ynylpyridine; 6-Prop-1-ynyl-2-fluoropyridine; 2-Fluoro-6-(1-propynyl)pyridine; 2-Fluoro-6-propynylpyridine; 2-Fluoro-6-(prop-1-ynyl)pyridine; 2-Fluoro-6-(prop-2-ynyl)pyridine (common misnomer); 2-Fluoro-6-(propyn-1-yl)pyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of Pyridine, 2-Fluoro-6-(1-Propynyl)- is analyzed using advanced techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system is designed to support cGMP and ISO standards for traceability and reliability in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.