Description

Azalanstat CAS NO 143393-27-5 is a high-purity, synthetic chemical compound belonging to the class of statin derivatives. This compound is of significant interest for its role as a key intermediate in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in developing treatments for metabolic and cardiovascular conditions.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel HMG-CoA reductase inhibitors and other statin-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or tool compound in metabolic pathway studies and enzyme inhibition assays within academic and industrial R&D laboratories.
• Process Development: Serves as a key starting material (KSM) or advanced intermediate for optimizing scalable manufacturing routes for target drug molecules.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	Azalanstat
CAS No.	143393-27-5
Molecular Formula	C25H27F2N3O4
Molecular Weight	471.50 g/mol
Synonyms	Azalanstat; (3R,5S)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methylsulfanyl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (E)-(3R,5S)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(methylthio)pyrimidin-5-yl]-3,5-dihydroxy-6-heptenoic acid; L-654,969; SQ 33,600; SQ-33600; SQ33600; AY-25,712.
EINECS	Contact for details

Quality Control

Our Azalanstat is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed-upon specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.