Description

17-Azaprostaglandin F2Alpha is a synthetic analog of prostaglandin F2α, where a nitrogen atom replaces a carbon in the cyclopentane ring, creating a unique aza-prostane structure. This modification is of significant interest in medicinal chemistry for developing novel pharmacological tools and potential therapeutic agents targeting prostanoid receptors. It is primarily utilized by research institutions and pharmaceutical companies engaged in cardiovascular, reproductive, and ocular physiology research, as well as in the development of new drug candidates.

Application

• Biomedical Research: Serves as a critical reference standard and active probe in studies of prostaglandin receptor (FP receptor) signaling pathways and biological functions.
• Pharmaceutical Development: Used as a key intermediate or lead compound in the synthesis and optimization of new drug candidates targeting intraocular pressure, uterine contraction, or other FP receptor-mediated processes.
• Biochemical Assays: Employed in in vitro and cell-based assays to investigate agonist/antagonist activity, receptor binding affinity, and downstream cellular responses.
• Metabolic Studies: Utilized to study the stability, metabolism, and pharmacokinetic profile of aza-prostane analogs compared to their native prostaglandin counterparts.

Basic Information

Product Name	17-Azaprostaglandin F2Alpha
CAS No.	143134-34-3
Molecular Formula	C₂₀H₃₅NO₅
Molecular Weight	369.50 g/mol
Synonyms	17-Aza-PGF2α; 17-Aza-prostaglandin F2α; 9α,11α,15S-Trihydroxy-17-aza-5-cis-13-trans-prostadienoic Acid; AZA-PGF2α; 17-Nitrogen-prostaglandin F2α Analog
EINECS	Contact for details

Quality Control

Our 17-Azaprostaglandin F2Alpha is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for advanced research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent internal quality standards, and specifications can be aligned with customer requirements for specific research or development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.