Description

Methyl 2-[[5-(Trifluoromethyl)-2-Pyridyl]Sulfonyl]Acetate is a high-value, specialized organic intermediate featuring a pyridine core with a trifluoromethyl and a sulfonylacetate ester group. This compound matters for its role as a critical building block in the synthesis of advanced molecules, particularly in the agrochemical and pharmaceutical sectors. It is primarily needed by R&D chemists and process development teams working on novel active ingredients, where its unique structure enables the introduction of key functional motifs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl and sulfone groups.
• Material Science Research: Used in the development of specialty polymers and functional materials where the sulfonyl and ester groups can be modified for specific properties.
• Ligand and Catalyst Development: The pyridine moiety makes it a useful starting material for creating novel ligands in coordination chemistry and catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	Methyl 2-[[5-(Trifluoromethyl)-2-Pyridyl]Sulfonyl]Acetate
CAS No.	142274-37-1
Molecular Formula	C9H8F3NO4S
Molecular Weight	283.22 g/mol
Synonyms	Methyl (5-(trifluoromethyl)pyridin-2-yl)sulfonylacetate; Acetic acid, 2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]-, methyl ester; Methyl 2-((5-(trifluoromethyl)pyridin-2-yl)sulfonyl)acetate; 2-Pyridinesulfonylacetic acid, 5-(trifluoromethyl)-, methyl ester; Methyl [5-(trifluoromethyl)pyridin-2-yl]sulfonylacetate
EINECS	Contact for details

Quality Control

Our Methyl 2-[[5-(Trifluoromethyl)-2-Pyridyl]Sulfonyl]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.