Description

3-(Chlorosulphonyl)-1-Methyl-1H-Pyrrole is a versatile and highly reactive pyrrole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the chlorosulphonyl group, which acts as a powerful electrophile for introducing the sulphonamide moiety, a key functional group in many active compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel sulfonamide-based active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating new generations of herbicides, fungicides, and insecticides with sulfonamide activity.
• Material Science Research: Used in the development of specialty polymers and functional materials requiring sulfonamide linkages.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers for bespoke molecule production.

Basic Information

Product Name	3-(Chlorosulphonyl)-1-Methyl-1H-Pyrrole
CAS No.	142112-64-9
Molecular Formula	C5H6ClNO2S
Molecular Weight	179.62 g/mol
Synonyms	1-Methyl-1H-pyrrole-3-sulfonyl chloride; 1-Methylpyrrole-3-sulfonyl chloride; 3-(Chlorosulfonyl)-1-methyl-1H-pyrrole; 1-Methyl-3-pyrrolesulfonyl chloride; N-Methyl-3-pyrrolesulfonyl chloride; 3-Chlorosulfonyl-1-methylpyrrole; Pyrrole-3-sulfonyl chloride, 1-methyl-
EINECS	Contact for details

Quality Control

Every batch of 3-(Chlorosulphonyl)-1-Methyl-1H-Pyrrole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and synthesis. A detailed Certificate of Analysis (COA), including assay (HPLC), identity confirmation (IR, NMR), and impurity profile, is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.